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GLP-1 receptor agonists (GLP-1RAs) help regulate hunger, fullness, and energy balance , the same signals that often become dysregulated in obesity. These medications work with your body’s natural hormones to make healthy changes easier, more achievable, and more sustainable.
Reduce Hunger & Cravings
GLP-1 medications work directly on the brain’s appetite centers, helping reduce constant hunger and food cravings that many people with obesity experience. By calming these signals, GLP-1RAs make it easier to feel satisfied with smaller portions and avoid overeating, even in situations that used to trigger strong cravings
Feel Full Longer
These medications slow the rate at which food leaves your stomach, allowing you to stay full for a longer period of time after meals. This leads to a natural reduction in calorie intake without needing extreme dieting or restrictive eating patterns, and it supports more consistent, controlled eating throughout the day.
Improve Metabolic Health
Beyond weight loss, GLP-1 medications help improve blood pressure, cholesterol, fatty liver disease, sleep apnea and inflammation. These changes reduce strain on the heart and support long-term wellness, making GLP-1 therapies a valuable option for individuals seeking sustainable improvements in their metabolic health.
Sustainable Weight Loss
Because GLP-1RAs reduce appetite and increase fullness, most people experience gradual, meaningful weight loss over time. Clinical studies show 10–15% average weight loss with semaglutide and even greater results with newer dual and triple agonists like tirzepatide and retatrutide. This weight loss improves overall metabolic health and reduces risks connected to obesity.
Who Benefits The Most
People with a BMI of 30 or higher, or 27 or higher with weight-related health issues such as high blood pressure or sleep apnea, often benefit the most from these medications.
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